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Daniele Ouellet Selected Research

erdafitinib

1/2022Erdafitinib's effect on serum phosphate justifies its pharmacodynamically guided dosing in patients with cancer.
1/2022Exposure-response analyses of erdafitinib in patients with locally advanced or metastatic urothelial carcinoma.
1/2020Population Pharmacokinetics of Total and Free Erdafitinib in Adult Healthy Volunteers and Cancer Patients: Analysis of Phase 1 and Phase 2 Studies.
1/2019Assessment of the effect of erdafitinib on cardiac safety: analysis of ECGs and exposure-QTc in patients with advanced or refractory solid tumors.

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Daniele Ouellet Research Topics

Disease

14Neoplasms (Cancer)
01/2022 - 06/2013
8Melanoma (Melanoma, Malignant)
04/2016 - 05/2012
3Body Weight (Weight, Body)
01/2020 - 06/2011
2Exanthema (Rash)
01/2020 - 07/2012
2Prostatic Neoplasms (Prostate Cancer)
01/2020 - 01/2020
2Fever (Fevers)
11/2014 - 11/2012
2Disease Progression
07/2012 - 04/2005
2Idiopathic Thrombocytopenic Purpura (Thrombocytopenic Purpura, Autoimmune)
10/2011 - 06/2011
2Osteoporosis
01/2006 - 12/2005
1Carcinoma (Carcinomatosis)
01/2022
1Neoplasm Metastasis (Metastasis)
01/2020
1COVID-19
01/2020
1Fatigue
01/2020
1Weight Loss (Weight Reduction)
01/2020
1Arthralgia (Joint Pain)
01/2020
1Squamous Cell Carcinoma (Epidermoid Carcinoma)
11/2014
1Thrombocytopenia (Thrombopenia)
06/2013
1Diarrhea
07/2012
1Edema (Dropsy)
07/2012
1Infections
06/2012
1Intraabdominal Infections
06/2012
1Brain Neoplasms (Brain Tumor)
05/2012
1Schizophrenia (Dementia Praecox)
12/2011
1Sleep Initiation and Maintenance Disorders (Insomnia)
10/2011
1Dizziness (Lightheadedness)
08/2010
1Sleepiness
08/2010
1Fibromyalgia (Fibrositis)
07/2010
1Pain (Aches)
07/2010
1Heart Failure
12/2005
1Neuralgia (Stump Neuralgia)
04/2005

Drug/Important Bio-Agent (IBA)

8dabrafenibIBA
04/2015 - 05/2012
6Pharmaceutical PreparationsIBA
12/2018 - 04/2005
6trametinibIBA
04/2016 - 07/2012
6Mitogen-Activated Protein Kinase Kinases (MEKs)IBA
04/2016 - 07/2012
4erdafitinibIBA
01/2022 - 01/2019
3ibrutinibIBA
10/2020 - 12/2017
3eltrombopagFDA Link
06/2013 - 06/2011
2Phosphates (Orthophosphate)IBA
01/2022 - 01/2022
2apalutamideIBA
01/2020 - 01/2020
2AlbuminsIBA
01/2020 - 01/2020
2Cytochrome P-450 CYP3A InhibitorsIBA
12/2018 - 04/2015
2Proto-Oncogene Proteins B-rafIBA
06/2014 - 09/2013
2Inosine Triphosphate (ITP)IBA
10/2011 - 06/2011
2LasofoxifeneIBA
01/2006 - 12/2005
1Biomarkers (Surrogate Marker)IBA
01/2022
1Bupropion (Wellbutrin)FDA LinkGeneric
10/2020
1Midazolam (Versed)FDA LinkGeneric
10/2020
1MacrolidesIBA
01/2020
1Blood Proteins (Serum Proteins)IBA
01/2020
1Anti-Bacterial Agents (Antibiotics)IBA
01/2020
1Androgen Receptors (Androgen Receptor)IBA
01/2020
1Azithromycin (Zithromax)FDA LinkGeneric
01/2020
1TrabectedinIBA
10/2019
1Voriconazole (Vfend)FDA LinkGeneric
12/2018
1Erythromycin (Erycette)FDA LinkGeneric
12/2018
1Agammaglobulinaemia Tyrosine KinaseIBA
12/2017
1Ketoconazole (Nizoral)FDA LinkGeneric
04/2015
1Warfarin (Coumadin)FDA LinkGeneric
04/2015
1Gemfibrozil (Lopid)FDA LinkGeneric
04/2015
1Cytochrome P-450 CYP2C9IBA
04/2015
1Cytochrome P-450 CYP2C8IBA
04/2015
1SaltsIBA
12/2013
1SulfonamidesIBA
12/2013
1CarbonIBA
12/2013
1NitrogenIBA
12/2013
1methanesulfonic acid (methanesulfonate)IBA
12/2013
1Capsules (Microcapsules)IBA
09/2013
1Paclitaxel (Taxol)FDA LinkGeneric
06/2013
1Thrombopoietin ReceptorsIBA
06/2013
1Carboplatin (JM8)FDA LinkGeneric
06/2013
1Protein Serine-Threonine Kinases (Protein-Serine-Threonine Kinase)IBA
07/2012
1PiperacillinFDA LinkGeneric
06/2012
1Glycine Plasma Membrane Transport ProteinsIBA
12/2011
1(1- aminomethyl- 3,4- dimethylcyclopentyl)acetic acidIBA
10/2011
1Hypnotics and Sedatives (Sedatives)IBA
10/2011
1Zolpidem (Ambien)FDA LinkGeneric
10/2011
1Lorazepam (Ativan)FDA LinkGeneric
08/2010
1CreatinineIBA
07/2010
1Pregabalin (Lyrica)FDA Link
07/2010
1Selective Estrogen Receptor Modulators (SERM)IBA
01/2006
1Digoxin (Digitek)FDA LinkGeneric
12/2005
1Gabapentin (Neurontin)FDA LinkGeneric
04/2005

Therapy/Procedure

3Drug Therapy (Chemotherapy)
06/2013 - 07/2012
2Castration
01/2020 - 01/2020
1Intravenous Infusions
10/2019
1Immunotherapy
02/2013
1Therapeutics
11/2012
1Drug Tapering
07/2012